Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens

DV Havlir, NS Hellmann, CJ Petropoulos, JM Whitcomb… - Jama, 2000 - jamanetwork.com
ContextLoss of viral suppression in patients infected with human immunodeficiency virus
(HIV), who are receiving potent antiretroviral therapy, has been attributed to outgrowth of
drug-resistant virus; however, resistance patterns are not well characterized in patients
whose protease inhibitor combination therapy fails after achieving viral suppression.
ObjectiveTo characterize drug susceptibility of virus from HIV-infected patients who are
failing to sustain suppression while taking an indinavir-containing antiretroviral regimen …