The mutability toward ultarviolet light of recombination-deficient strains of Escherichia coli
EM Witkin - … Research/Fundamental and Molecular Mechanisms of …, 1969 - Elsevier
Strains having recA and recC mutations were tested for UV mutability. A recA strain is UV-
stsable at doses that are demonstrably mutagenic in its Rec+ derivative. Strains of recC
genotype are not UV-stable, but produce UV-induced mutations at frequencies significantly
lower than those produced at the same doses in Rec+ strains. The results support the
hypothesis that most UV-induced mutations originate as errors in recombinational repair of
single-strand gaps in DNA.
stsable at doses that are demonstrably mutagenic in its Rec+ derivative. Strains of recC
genotype are not UV-stable, but produce UV-induced mutations at frequencies significantly
lower than those produced at the same doses in Rec+ strains. The results support the
hypothesis that most UV-induced mutations originate as errors in recombinational repair of
single-strand gaps in DNA.
