A compound capable of preventing age-related hearing loss would be very useful in an
aging population. N-acetyl-l-cysteine (l-NAC) has been shown to be protective against noise
exposure, a condition that leads to increased oxidative stress. Not withstanding
environmental factors, there is evidence that age-related hearing loss (AHL) in the mouse is
linked to more than one genetic loci and, by extension, in humans. Our hypothesis is that
AHL defect results in increased sensitivity to oxidative stress and l-NAC would be able to …