[HTML][HTML] Monoamine oxidase A suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling
J Li, XM Yang, YH Wang, MX Feng, XJ Liu… - Journal of …, 2014 - Elsevier
Background & Aims Monoamine oxidase A (MAOA), a catecholamine neurotransmitter
degrading enzyme, is closely associated with neurological and psychiatric disorders.
However, its role in cancer progression remains unknown. Methods Hepatocellular
carcinoma (HCC) tissue arrays (n= 254) were used to investigate the correlation between
MAOA expression and clinicopathological findings. In vitro invasion and anoikis assays, and
in vivo intrahepatic and lung metastasis models were used to determine the role of MAOA in …
degrading enzyme, is closely associated with neurological and psychiatric disorders.
However, its role in cancer progression remains unknown. Methods Hepatocellular
carcinoma (HCC) tissue arrays (n= 254) were used to investigate the correlation between
MAOA expression and clinicopathological findings. In vitro invasion and anoikis assays, and
in vivo intrahepatic and lung metastasis models were used to determine the role of MAOA in …