Pathologic changes in the renal tubule in systemic lupus erythematosus
MM Schwartz, JS Fennell, EJ Lewis - Human Pathology, 1982 - Elsevier
Interstitial nephritis may be a prominent morphologic feature in systemic lupus
erythematosus (SLE), but there are limited data relating the pathologic findings to renal
function impairment. We studied 69 biopsy specimens from 55 patients by light,
fluorescence, and electron microscopy and compared the results with the serum creatinine
levels. The relative interstitial volume, a measure of tubular damage and interstitial
expansion, was the only morphologic feature that correlated well with renal function (serum …
erythematosus (SLE), but there are limited data relating the pathologic findings to renal
function impairment. We studied 69 biopsy specimens from 55 patients by light,
fluorescence, and electron microscopy and compared the results with the serum creatinine
levels. The relative interstitial volume, a measure of tubular damage and interstitial
expansion, was the only morphologic feature that correlated well with renal function (serum …