Mast cell surfaceome characterization reveals CD98 heavy chain is critical for optimal cell function

SS Saha, NB Samanas, I Miralda, NJ Shubin… - Journal of Allergy and …, 2022 - Elsevier
Background Mast cells are involved in many distinct pathologic conditions, suggesting that
they recognize and respond to various stimuli and thus require a rich repertoire of cell
surface proteins. However, mast cell surface proteomes have not been comprehensively
characterized. Objective We aimed to further characterize the mast cell surface proteome to
obtain a better understanding of how mast cells function in health and disease. Methods We
enriched for glycosylated surface proteins expressed in mouse bone marrow–derived …