Pancreatic islet cell development and regeneration
AI Romer, L Sussel - Current Opinion in Endocrinology, Diabetes …, 2015 - journals.lww.com
AI Romer, L Sussel
Current Opinion in Endocrinology, Diabetes and Obesity, 2015•journals.lww.comThe overall conservation between mouse and human pancreatic development, islet
physiology and etiology of diabetes encourages the translation of novel β cell replacement
therapies to humans. Further deciphering the molecular mechanisms that direct islet cell
regeneration, plasticity and function could improve and expand the β cell replacement
strategies for treating diabetes.
physiology and etiology of diabetes encourages the translation of novel β cell replacement
therapies to humans. Further deciphering the molecular mechanisms that direct islet cell
regeneration, plasticity and function could improve and expand the β cell replacement
strategies for treating diabetes.
Summary
The overall conservation between mouse and human pancreatic development, islet physiology and etiology of diabetes encourages the translation of novel β cell replacement therapies to humans. Further deciphering the molecular mechanisms that direct islet cell regeneration, plasticity and function could improve and expand the β cell replacement strategies for treating diabetes.
Lippincott Williams & Wilkins