The impact of sex and sex hormones on lung physiology and disease: lessons from animal studies

MA Carey, JW Card, JW Voltz… - … of Physiology-Lung …, 2007 - journals.physiology.org
MA Carey, JW Card, JW Voltz, DR Germolec, KS Korach, DC Zeldin
American Journal of Physiology-Lung Cellular and Molecular …, 2007journals.physiology.org
Numerous animal studies have revealed significant effects of sex and sex hormones on
normal lung development, lung physiology, and various lung diseases. The primary goal of
this review is to summarize knowledge to date on the effects of sex and sex hormones on
lung development, physiology, and disease in animals. Specific emphasis will be placed on
fibrosis, allergic airway disease, acute lung injury models, respiratory infection, and lung
toxicology studies.
Numerous animal studies have revealed significant effects of sex and sex hormones on normal lung development, lung physiology, and various lung diseases. The primary goal of this review is to summarize knowledge to date on the effects of sex and sex hormones on lung development, physiology, and disease in animals. Specific emphasis will be placed on fibrosis, allergic airway disease, acute lung injury models, respiratory infection, and lung toxicology studies.
American Physiological Society